Xiaflex approved by FDA for treatment of Peyronie’s disease
Last week many media outlets covered the approval of a drug called Xiaflex (collagenase Clostridium histolyticum) for the non-surgical treatment of Peyronie’s disease. Peyronie’s disease can occur as a...
View ArticleGenomics, prostate cancer, and biomarker development
A number of readers may be interested in an article by Yadav et al. in the January issue of AUA News, entitled “Genomics at the forefront of biomarker development for prostate cancer detection and...
View ArticleCustom treatment for high-risk forms of prostate cancer
There’s a long article by Ron Winslow in the Wall Street Journal today about the potential for “custom-treatment” of men with aggressive and less aggressive forms of high-risk prostate cancer. While...
View ArticleBill Manning’s blog: Introduction and Part I
This is the beginning of a proposed series of blog posts by a patient with serious, advanced prostate cancer. He, and we, hope it will be helpful to all those battling late stage prostate cancer as he...
View ArticleUroToday interviews with D’Amico, Klotz, Mulhall
Many readers of this blog may be interested in listening to one or more of a series of recent, relatively short audio-interviews with respected opinion-leaders in the prostate cancer diagnosis and...
View Article10-year survival data from the RT01 trial of differing doses of 3D-CRT
According to a paper just published in Lancet Oncology today, the 10-year follow-up results of the RT01 trial carried out under the auspices of the British Medical Research Council have shown an...
View Article“Five golden rules” for prostate cancer screening and treatment today
In a very simple and straightforward article in European Urology, Vickers et al. have clearly laid out a series of five “golden rules” that, in their opinion, all physicians should be following today...
View ArticlePrimary ADT ineffective for most men with early stage prostate cancer
Data from a large, retrospective study, reported in the Journal of Clinical Oncology, suggest something that many expert clinicians and patients have long suspected … that early use of androgen...
View ArticleNew Phase I/II trial of InSightec’s MRI-guided focal ultrasound therapy
According to a media release issued yesterday by the City of Hope medical center in Los Angeles, they have become the first center in the USA to treat a patient with focused, MRI-guided, ultrasound...
View Article“Best care” doesn’t equate to better outcomes! That’s not good!
A poster by Schroeck et al. — to be presented on May 20 at the upcoming annual meeting of the American Urological Association (AUA) — presents the latest set of data suggesting that “best care” does...
View ArticleThe benefit (or lack thereof) of early, aggressive treatment in men ≥ 66 years
A new study published on line in the journal Cancer has shown that (a) the cancer-specific survival benefit associated with aggressive treatment for early-stage prostate cancer is reduced with...
View ArticleTime to prove a treatment-related prostate cancer survival benefit
For most of the past 20 years it has generally been considered that it took 10 years to show that a new form of therapy was effective and safe in the treatment of localized prostate cancer. We may need...
View ArticleLow insurance, high risk (for prostate cancer mortality among African Americans)
A recently published paper in the journal Urologic Oncology has confirmed that (regrettably but unsurprisingly), here in the USA, African-American men with high-risk prostate cancer are significantly...
View ArticleAntioxidants and cancer: do they, could they really work?
For much of the past 30 years or so there has been a great deal of effort to try to prove that antioxidants — and most specifically dietary antioxidants like some vitamins — can be used to either...
View ArticleIf you’re already depressed, you may need help to make good decisions
In a rather less that surprising finding, a new paper in the Journal of Clinical Oncology reports that men with existing depressive disorders at the time of diagnosis with prostate cancer “are less...
View ArticlePhysicians’ attitudes and the management of low-risk prostate cancer in older...
According to newly published data in JAMA Internal Medicine and discussed on the Reuters web site today, “physician characteristics may play a larger role than disease characteristics when it comes to...
View ArticleQuality of life after standard therapies for localized prostate cancer
Assessment of patient quality of life (QoL) after standard forms of treatment for localized prostate cancer is difficult for many reasons — not least because there is no real agreement among members of...
View ArticleLearning to live with the “new normal”… or avoid it if you can
Very, very, very slowly it appears that we are starting to see some serious interest in research into the psychosocial impact of prostate cancer and its treatment on men and their close family members...
View ArticleThe less you know, the harder the decisions about treatment …
In one more of those utterly unsurprising research findings, a study of newly diagnosed patients has shown that poor patient knowledge about the nature of prostate cancer is associated with “decisional...
View ArticleAddressing “sex vs. death” perceptions in prostate cancer treatment
The following is the full text of an article by Anne Katz, RN, PhD, who is a Clinical Nurse Specialist and AASECT-Certified Sexuality Counselor who blogs at ASCO Connection, where this post originally...
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